Pyrroloquinoline and piperidoquinoline derivatives,...

Details Pyrroloquinoline and piperidoquinoline derivatives,... Pyrroloquinoline and piperidoquinoline derivatives,...

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/4745 (2006.01) A61P 25/04 (2006.01) A61P 29/00 (2006.01)

Patent

CA 2555491

Compounds of general formula (I) wherein n, R1, R2, R3, R4 and Ar are as defined in the specification, as well as salts, enantiomers thereof and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain.

L'invention se rapporte à la préparation des composés de la formule générale (1), dans laquelle n, R?1¿, R?2¿, R?3¿, R?4¿ et Ar sont tels que définis dans la spécification, et de sels, d'énantiomères de ces derniers et de compositions pharmaceutiques contenant lesdits composés. Les composés de l'invention sont utilisés en thérapie, en particulier dans le soulagement de la douleur.

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