Pyrrolotriazine aniline prodrug compounds useful as kinase...

Details Pyrrolotriazine aniline prodrug compounds useful as kinase... Pyrrolotriazine aniline prodrug compounds useful as kinase...

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/53 (2006.01) A61P 29/00 (2006.01) C07C 11/00 (2006.01)

Patent

CA 2645031

Compounds having the Formula (I), including pharmaceutically acceptable salts thereof, wherein at least one of X1, X2 or X3 is (i), and any remaining X1, X2 or X3 is hydrogen, which are useful as kinase inhibitors, wherein R1, R2, R3, R4, R5, R6, A1, A2 and m are as described herein.

La présente invention concerne des composés répondant à la formule (I), incluant des sels pharmaceutiquement acceptables de ceux-ci, [INSERER LA FORMULE CHIMIQUE ICI] (I), dans laquelle au moins un élément choisi parmi X1, X2 ou X3 représente [INSERER LA FORMULE CHIMIQUE ICI] (i), et tout élément restant X1, X2 ou X3 est un atome d'hydrogène, qui sont utiles en tant qu'inhibiteurs de kinase, dans laquelle R1, R2, R3, R4, R5, R6, A1, A2 et m sont tels que décrits dans le présent document.

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