Pyruvate carboxylase from corynebacterium glutamicum

Details Pyruvate carboxylase from corynebacterium glutamicum Pyruvate carboxylase from corynebacterium glutamicum

C - Chemistry, Metallurgy

12

N

C12N 15/52 (2006.01) C12N 9/00 (2006.01) C12P 13/08 (2006.01)

Patent

CA 2356446

The present invention concerns an anaplerotic enzyme from Corynebacterium glutamicum which replenishes oxaloacetate consumed during lysine and glutamic acid production in industrial fermentations. In particular, isolated nucleic acid molecules are provided encoding the pyruvate carboxylase protein. Pyruvate carboxylase polypeptides are also provided.

L'invention concerne une enzyme anaplérotique provenant de Corynebacterium glutamicum, qui reconstitue l'oxaloacétate consommé durant la production de lysine et d'acide glutamique durant les fermentations industrielles. Elle concerne notamment des molécules d'acide nucléique qui codent pour la protéine pyruvate carboxylase, ainsi que des polypeptides de ladite pyruvate carboxylase.

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