Q3 sparc deletion mutant and uses thereof

Details Q3 sparc deletion mutant and uses thereof Q3 sparc deletion mutant and uses thereof

C - Chemistry, Metallurgy

07

K

C07K 14/47 (2006.01) A61K 38/39 (2006.01) A61K 39/395 (2006.01)

Patent

CA 2598510

The invention provides for SPARC polypeptides with a mutation corresponding to a deletion of the third glutamine in the mature form of the human SPARC protein, nucleic acids encoding such polypeptides, antibodies against such polypeptides, and methods of the use of such polypeptides, nucleic acids, and antibodies.

La présente invention concerne des polypeptides SPARC présentant une mutation qui correspond à une délétion de la troisième glutamine dans la forme mature de la protéine SPARC humaine, des acides nucléiques codant ces polypeptides, des anticorps contre ces polypeptides et des méthodes d'utilisation de ces polypeptides, acides nucléiques et anticorps.

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