C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) C12P 19/34 (2006.01)
Patent
CA 2542656
The invention concerns an integrated, qRT-PCR-based system for analyzing and reporting RNA expression profiles of biological samples. In particular, the invention concerns a fully optimized and integrated multiplex, multi-analyte method for expression profiling of RNA in biological samples, including fixed, paraffin-embedded tissue samples. The gene expression profiles obtained can be used for the clinical diagnosis, classification and prognosis of various pathological conditions, including cancer.
L'invention concerne un système intégré utilisant le procédé qRT-PCR en vue de l'analyse et du rapport des profils d'expression d'ARN d'échantillons biologiques. L'invention concerne plus particulièrement un procédé à multiples substances à analyser multiplex intégré et totalement optimisé permettant le profilage de l'expression d'ARN dans des échantillons biologiques, y compris des échantillons de tissus enrobés de paraffine fixes. Les profils d'expression génétique obtenus peuvent être utilisés pour le diagnostic clinique, la classification et le pronostic de différentes pathologies, y compris le cancer.
Baker Joffre B.
Clark Kim
Cronin Maureen T.
Kiefer Michael C.
Li Xitong
Genomic Health Inc.
Smart & Biggar
LandOfFree
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