A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/39 (2006.01) A61K 39/102 (2006.01)
Patent
CA 2409406
Adjuvant compositions comprising an effective amount IL-12 and QS-21 are disclosed. Immunogenic, vaccine and pharmaceutical compositions comprising a mixture of antigen and an adjuvant composition comprising an effective amount of IL-12 and QS-21 are also disclosed. These compositions elicit functional cell-mediated and humoral immune responses against at least one antigen. Methods of using the disclosed compositions are also disclosed.
Cette invention se rapporte à des compositions d'adjuvants qui comprennent une quantité efficace d'IL-12 et de QS-21. Des compositions immunogènes, de vaccins et pharmaceutiques comprenant un mélange d'antigène et d'une composition d'adjuvant contenant une quantité efficace d'IL-12 et de QS-21 sont également décrites. Ces compositions déclenchent des réactions immunitaires humorales et à médiation cellulaire fonctionnelle contre au moins un antigène. Des procédés d'utilisation de ces compositions sont également décrits.
American Cyanamid Company
Smart & Biggar
Wyeth Holdings Corporation
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