Qt dispersion and heart rate variability improvement with...

Details Qt dispersion and heart rate variability improvement with... Qt dispersion and heart rate variability improvement with...

A - Human Necessities

61

K

A61K 31/52 (2006.01) A61K 31/437 (2006.01) A61K 31/44 (2006.01) A61K 31/455 (2006.01) A61K 31/505 (2006.01) A61K 31/506 (2006.01) A61K 31/519 (2006.01)

Patent

CA 2303577

Disclosed is a medicine for preventing sudden death of a mammal, including a human, which comprises (a) a therapeutically effective amount of a corticotropin releasing factor (CRF) antagonist and (b) a pharmaceutically acceptable carrier. The CRF antagonist may be a compound of the formula: (see above formula) (wherein A is CH, N, etc.; B is NH2 or the like; D is N, CH, etc.; E is N, CH, etc.; Y is N or CH; Z is NH, O, S, CH2, etc.; R3 is H, alkyl, etc.; R4 is H, alkyl, etc.; and R5 is a ring).

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