Quadrupole mass spectrometer with ion traps to enhance...

H - Electricity – 01 – J

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H01J 49/42 (2006.01) H01J 49/26 (2006.01)

Patent

CA 2375194

A mass spectrometer method and apparatus has a mass analyzer and a collision cell. The collision cell is configured to trap ions. Precursor ions are selected in the first mass analyzer and then subject to collision-induced dissociation in the collision cell. The fragment ions are then scanned outaxially by application of suitable excitation to the ions. The fragment ions can then be detected by a time of flight (TOF) mass spectrometer. For a TOF spectrometer, trapping fragment ions in the collision cell and scanning them out can give enhanced sensitivity.

La présente invention concerne un procédé et un dispositif de spectrométrie de masse. Ledit dispositif est doté d'un analyseur de masse et d'une cellule de collision configurée pour piéger les ions. Les ions précurseurs sont sélectionnés dans le premier analyseur de masse puis subissent une dissociation par collision à l'intérieur de la cellule de collision. Les ions fragments subissent alors un balayage axial par application d'une excitation adaptée aux ions. Les ions fragments peuvent alors être détectés par un spectromètre de masse à durée de trajet (time of flight / TOF). Le piégeage d'ions fragments dans la cellule de collision et leur balayage peuvent donner au spectromètre TOF une meilleure sensibilité.

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