Quality assays for antigen presenting cells

C - Chemistry – Metallurgy – 12 – Q

Patent

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Details

C12Q 1/00 (2006.01) C12Q 1/02 (2006.01) G01N 1/30 (2006.01) G01N 33/48 (2006.01) G01N 33/569 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2484743

The present invention provides methods for evaluating the quality of a preparation of antigen presenting cells, such as dendritic cells. Assays for antigen-independent co-stimulation of T cells and for presentation of predetermined antigen by APC's are provided.

La présente invention concerne des méthodes qui permettent d'évaluer la qualité d'une préparation de cellules de présentation d'antigènes (APC), telles que des cellules dendritiques; ainsi que des dosages utiles pour la co-stimulation indépendamment des antigènes de cellules T et pour la présentation d'antigènes prédéterminés par les APC.

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