Quantification of fibrinogen in whole blood samples

G - Physics – 01 – N

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G01N 33/86 (2006.01) G01N 15/04 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2042434

INVENTORS: Robert A. Levine Allan H. Hart Stephen C. Wardlaw TITLE: "QUANTIFICATION OF FIBRINOGEN IN WHOLE BLOOD SAMPLES" DOCKET NO: H-1179 ABSTRACT OF THE DISCLOSURE Quantification of blood plasma fibrinogen content is made in a sample ofanticoagulated whole blood contained in a sampling tube. The tube is a transparent centrifuge tube which contains a sample constituent layer-elongating float. The blood sample is centrifuged in the tube containing the float, and various cell constituent measurements are made. The centrifuged sample is then heated and recentrifuged to cause the precipitated fibrinogen to layer out on top of the float remote from the buffy coat band in the plasma layer. The thickness of the fibrinogen band is then measured, whereby quantification of the fibrinogen content of the blood sample can be made by a precalibrated instrument.

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