Quantitative analysis for diabetic condition predictor

G - Physics – 01 – N

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G01N 33/74 (2006.01) G01N 33/543 (2006.01) G01N 33/66 (2006.01)

Patent

CA 2051630

-10- Quantitative Analysis For Diabetic Condition Predictor Abstract An enhanced quantitative assay for chiro-inositol concentration can be used to determine insulin-resistance, or a predisposition to the development of insulin- resistance, in type I and type II diabetics. Spot urine or serum samples reflecting concentrations of chiro- inositol below about 1.0 micrograms/ml in urine or 0.1 micrograms/ml in serum are indicative of a predisposition to the development of insulin-resistance, while concentrations below about 0.3 micrograms/ml or 0.03 micrograms/ml in serum are associated with actual insulin- resistance symptoms. The assay can be employed for patient diagnosis, insulin therapy monitoring, and family screening.

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