Quantitative analysis of a biological sample of unknown...

G - Physics – 01 – N

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G01N 33/92 (2006.01) B01L 3/00 (2006.01) G01N 33/48 (2006.01) G01N 33/574 (2006.01) G01N 33/96 (2006.01)

Patent

CA 2488933

Disclosed is a method for testing a modified specimen such as a dried blood spot, plasma or serum specimen, for an analyte of interest, such as cholesterol. In accordance with the disclosed subject matter, the level of the analyte of interest in the medium from which the modified specimen was obtained (e.g., from a patient's blood) is determined based on the level of an analyte in a solution formed from the modified specimen and on the level of at least one normalizing analyte. The analyte and normalizing analyte each may be an ion, compound, biochemical entity, or property of the specimen. Also disclosed are a fluid collector and a fluid collection device.

L'invention concerne un procédé permettant d'analyser un spécimen modifié tel qu'un spécimen de cellule sanguine séchée, de plasma ou de sérum pour un analyte d'intérêt, tel que le cholestérol. Selon l'invention, on détermine le niveau de l'analyte d'intérêt dans le milieu à partir duquel on a obtenu le spécimen modifié (par exemple, à partir du sang d'un patient) en fonction du niveau d'analyte dans une solution formée à partir du spécimen modifié et du niveau d'au moins un analyte de normalisation. L'analyte et l'analyte de normalisation peuvent chacun être un ion, un composé, une entité biochimique ou une propriété du spécimen. L'invention concerne également un collecteur de fluide et un dispositif de collecte de fluide.

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