Quantitative proteomics via isotopically differentiated...

C - Chemistry – Metallurgy – 40 – B

Patent

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C40B 40/04 (2006.01) C12Q 1/00 (2006.01) C12Q 1/34 (2006.01) C40B 30/10 (2006.01) C40B 40/10 (2006.01) C40B 70/00 (2006.01) G01N 27/00 (2006.01) G01N 33/68 (2006.01) H01J 49/00 (2006.01)

Patent

CA 2393726

A method for the quantitative analysis of a plurality of samples containing amines, particularly primary or secondary amines, by mass spectrometry is disclosed. The method involves the chemical of amines in the sample by reacting the samples with isotopically labelled reagents, resulting in the isotopic labelling of the alklyamine derivatives. The method allows for the simultaneous examination and analysis of a plurality of samples. The method is particularly useful in the field of proteomics.

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