Quarternary ammonium compounds as anti-tussive agents

C - Chemistry – Metallurgy – 07 – D

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C07D 209/08 (2006.01) A61K 31/40 (2006.01) C07C 237/04 (2006.01)

Patent

CA 2334454

Novel compounds and pharmaceutical compositions containing such compounds and possessing anti-tussive activity, formula (I), or a solvate or pharmaceutically acceptable salt thereof, wherein Y and E are independently selected from -CH2-R16 or a group represented by formula (II).

Cette invention se rapporte à de nouveaux composés ou à un solvate ou sel de ceux-ci acceptable sur le plan pharmaceutique et à des compositions pharmaceutiques contenant ces composés et possédant un effet antitussif, ces composés étant représentés par la formule (I), où Y et E sont choisis séparément entre -CH¿2?-R¿16? ou un groupe représenté par la formule (II).

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