Quaternary ammonium antiarrhythmic drugs

C - Chemistry – Metallurgy – 07 – D

Patent

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260/290.2, 260/3

C07D 295/00 (2006.01) A61K 31/135 (2006.01) C07C 217/62 (2006.01) C07D 295/037 (2006.01)

Patent

CA 1093072

Abstract Novel quaternary ammonium salts of certain phenylpropylamines and phenylbutylamines are dis- closed. They are useful drugs for treating arrhythmia and prolonging the action potential of cardiac muscle. They are prepared by reacting a tertiary amine with an alkyl salt.

317877

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