Quaternary ammonium compounds and their use as...

C - Chemistry – Metallurgy – 07 – D

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C07D 295/096 (2006.01) A61K 31/40 (2006.01) A61P 11/02 (2006.01) A61P 11/06 (2006.01) A61P 13/00 (2006.01) C07C 215/66 (2006.01)

Patent

CA 2522102

Novel quaternary ammonium compounds of the formula and any stereoisomers thereof, wherein R1, R2 R3, R4, R5, R6, R7, and X- are defined herein. The compounds are useful as medicaments for treatment of treatment of asthma, a group of breathing disorders termed Chronic Obstructive Pulmonary Disease (COPD), allergic rhinitis, rhinorrhea due to the common cold, and urinary disorder.

L'invention concerne de nouveaux composés d'ammonium quaternaire de la formule (I) dans laquelle R¿1?, R¿2?, R¿3?, R¿4?, R¿5?, R¿6?, R¿7?, et X?-¿ sont tels que définis dans le présent fascicule. L'invention concerne également n'importe quel stéréoisomère desdits composés qui sont utiles comme médicaments pour traiter l'asthme, un ensemble d'affections respiratoires appelé bronchopneumopathie chronique obstructive (BPCO), la rhinite allergique, la rhinorrhée due au rhume de cerveau, et l'uropathie.

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