Quaternary ammonium compounds and their use as anti-tussive...

C - Chemistry – Metallurgy – 07 – C

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C07C 217/14 (2006.01) A61K 31/135 (2006.01) A61P 11/14 (2006.01) C07C 217/18 (2006.01) C07C 217/30 (2006.01) C07D 209/08 (2006.01) C07D 211/14 (2006.01)

Patent

CA 2393699

In one aspect, the present invention concerns the use of certain quaternary ammonium compounds as active ingredient in the manufacture of a medicament for use in the treatment and/or prevention of cough in warm-blooded animals, including humans, such as compounds of formula Y-J-E An- (I), wherein J is independently selected from a group represented by one of formulae (II), (III) and (IV).

Un mode de réalisation de la présente invention concerne l'utilisation de certains composés d'ammonium quaternaire comme substance active intervenant dans la fabrication d'un médicament servant au traitement et/ou à la prévention de la toux chez des animaux à sang chaud, y compris chez l'être humain, les composés étant représentés par la formule (I), dans laquelle J est indépendamment choisi parmi un représenté par l'une des formules (II), (III) et (IV).

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