Quaternary ammonium salts as m3 antagonists

Details Quaternary ammonium salts as m3 antagonists Quaternary ammonium salts as m3 antagonists

C - Chemistry, Metallurgy

07

D

C07D 413/12 (2006.01) A61K 31/42 (2006.01) A61K 31/454 (2006.01) A61K 31/497 (2006.01) A61K 31/53 (2006.01) A61P 11/08 (2006.01) C07D 403/12 (2006.01) C07D 413/14 (2006.01)

Patent

CA 2589133

Compounds of formula (I), in salt or zwitterionic form, wherein J, L, M, R1, R2, R3, R4 and R5 have the meanings as indicated in the specification, are useful for treating conditions that are mediated by the muscarinic M3 receptor. Pharmaceutical compositions that contain the compounds and a process for preparing the compounds are also described.

L'invention concerne des composés de formule (I), sous forme de sel ou zwitterionique, J, L, M, R1, R2, R3, R4et R5 prenant la valeur indiquée dans la description. Ces composés sont utilisés dans le traitement de troubles induits par le récepteur M3 muscarinique. L'invention concerne également des compositions pharmaceutiques contenant ces composés et un procédé de préparation de ces composés.

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