Quaternary ammonium salts derived from chitosan

Details Quaternary ammonium salts derived from chitosan Quaternary ammonium salts derived from chitosan

C - Chemistry, Metallurgy

08

L

C08L 5/08 (2006.01) C08B 37/08 (2006.01) A61K 31/73 (1995.01)

Patent

CA 2092401

Quaternary ammonium salts of chitosan possessing hypocholesterolemic activity of formula (II) in which A represents the monomer unit of a chitosan, m is a whole number between 100 and 1,000. R1 is C1-C4 linear alkyl and Xn- is a physiologically acceptable water soluble polyanion, where n is at least 10 but not greater than about 10,000, and any remaining positive charges are balanced by nonpolymeric anions.

Sels d'ammonium quaternaire du chitosane possédant une activité hypocholestérolémique de formule (II) où A représente le monomère d'un chitosane, m est un nombre entier compris entre 100 et 1 000. R1 est un alkyle linéaire en C1-C4 et Xn- est un polyanion hydrosoluble physiologiquement acceptable, où n a une valeur d'au moins 10 sans toutefois excéder environ 10 000, et toute charge positive restante est équilibrée par des anions non polymériques.

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