Quaternary ammonium salts of natural polysaccharides...

Details Quaternary ammonium salts of natural polysaccharides... Quaternary ammonium salts of natural polysaccharides...

C - Chemistry, Metallurgy

08

B

167/199, 260/212

C08B 15/06 (2006.01) C08B 11/145 (2006.01) C08B 37/00 (2006.01)

Patent

CA 1282062

ABSTRACT Quaternary ammonium salts of natural polysaccharides possessing hypocholesterolemic activity, of the following general formula: Image X(-) (I) in which A represents the monomer unit of a natural polysaccha- ride, m is a whole number between 100 and 1000, n is a whole number between 0 and 10, B is O or S or NH or NR' where R' is an acyl and preferably an acetyl, R is a linear alkyl radical of 1-4 carbon atoms, and X(-) is an anion such as Cl-, Br-, I-, HSO4-, CH3O-SO3-, NO3- or the negative ion of a pharmaceutically acceptable organic acid. Said salts are prepared by reacting a pretreated natural polysac- charide with a quaternary ammonium salt functionalised at one of its ends with an epoxy group.

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