Quaternary compounds comprising propolis as the active...

A - Human Necessities – 61 – K

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A61K 9/14 (2006.01) A61K 8/44 (2006.01) A61K 8/63 (2006.01) A61K 8/73 (2006.01) A61K 8/98 (2006.01) A61K 9/00 (2006.01) A61K 9/46 (2006.01) A61Q 11/00 (2006.01) A61Q 19/00 (2006.01)

Patent

CA 2508034

The present invention describes a quaternary composition consisting of propolis delivered in a hydrophilic carrier (cyclodextrin and cyclodextrin derivatives) and co~ ground with the aid of two compounds for the preparation thereof in the form of a finely divided powder. The composition exhibits advantageous dissolution characteristics in aqueous environments compared to native propolis, hence resulting in greater bioavailability of the active ingredients contained therein.

L'invention concerne une composition quaternaire constituée de propolis libéré dans un excipient hydrophile (des dérivés de cyclodextrine et de cyclodextrine) et comoulu au moyen de deux composés pour leur préparation sous forme de poudre finement divisée. Cette composition présente des caractéristiques de dissolution avantageuses dans des environnements aqueux par rapport à propolis native, obtenant donc plus de biodisponibilité des ingrédients actifs contenus dans ce composé.

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