Quaternary salts of n-substituted cyclic or acyclic amines...

C - Chemistry – Metallurgy – 07 – D

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C07D 295/195 (2006.01) A61K 31/16 (2006.01) A61P 11/14 (2006.01) C07C 219/14 (2006.01) C07C 219/26 (2006.01) C07C 229/60 (2006.01) C07C 229/64 (2006.01) C07C 237/34 (2006.01) C07D 295/08 (2006.01) C07D 295/088 (2006.01) C07D 295/10 (2006.01) C07D 295/13 (2006.01) C07D 295/18 (2006.01)

Patent

CA 2393711

In one aspect, the present invention concerns the use of certain quaternary ammonium compounds as active ingredient in the manufacture of a medicament for use in the treatment and/or prevention of cough in warm-blooded animals, including humans, such as compounds of the following formula (I): Y.mdash. J.mdash. E An- wherein J is independently selected from a group represented by one of formulae (II), (III) and (IV).

L'invention concerne, dans une réalisation, l'utilisation de certains composés à ammonium quaternaire comme principes actifs dans la fabrication d'un médicament destiné à être utilisé dans le traitement et/ou la prévention de la toux chez les animaux à sang chaud, y compris chez les humains, tels que des composés représentés par la formule (I): Y.mdash. J.mdash. E An¿-? dans laquelle J est choisi de manière indépendante parmi l'une des trois formules suivantes (II), (III) et (IV).

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