Quick-dissolution solid preparation

Details Quick-dissolution solid preparation Quick-dissolution solid preparation

A - Human Necessities

61

K

A61K 47/38 (2006.01) A61K 9/16 (2006.01) A61K 9/20 (2006.01) A61K 31/40 (2006.01)

Patent

CA 2108374

ABSTRACT The invention provides a solid preparation having a quick and pH-independent dissolution with an excellent bioavailability for a drug that is otherwise sharply depressed in solubility with pH elevation. This solid preparation contains granules each comprising a fine particulate core coated with a solid solution comprising a drug which is pH-dependent in solubility and may be released from an enteric base- containing composition at low pH and an enteric base.

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