Quinazol in-2-ones

Details Quinazol in-2-ones Quinazol in-2-ones

C - Chemistry, Metallurgy

07

D

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C07D 239/74 (2006.01) C07C 45/71 (2006.01) C07C 273/18 (2006.01) C07D 239/80 (2006.01) C07C 275/50 (2006.01)

Patent

CA 1138871

ABSTRACT OF THE DISCLOSURE Compounds of the formula Image wherein R1 is hydrogen; alkyl having 4-20 carbons; cyclo- alkyl, heterocycloalkyl; halo; COO loweralkyl; CN; COOH; CH2OH; CH(O-loweralkyl)2 or nitro; and X and Y are each hydrogen; halo; nitro; loweralkyl; loweralkoxy; aryl; arylalkyloxy; hydroxy; acyloxy; aryloxy; amino; loweralkyl- amino; diloweralkylamino; amido; loweralkylamido; diloweralkyl- amido; cyano; COOH; COO loweralkyl; CHO; CH2OH; CH2O acyl; or CH2O aryl. The compounds find use in the treatment of hypertension and bradycardia and as a cardiotonic agent.

341352

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