Quinazoline based egfr inhibitors

Details Quinazoline based egfr inhibitors Quinazoline based egfr inhibitors

C - Chemistry, Metallurgy

07

D

C07D 239/94 (2006.01) A61K 31/517 (2006.01)

Patent

CA 2662587

The present invention relates to quinazoline containing zinc-binding moiety based derivatives that have enhanced and unexpected properties as inhibitors of epidermal growth factor receptor tyrosine kinase (EGFR-TK) and their use in the treatment of EGFR-TK related diseases and disorders such as cancer.

La présente invention concerne des dérivés à base de quinazoline contenant un fragment de liaison au zinc, qui présentent des propriétés améliorées et inattendues en tant qu'inhibiteurs de la tyrosine kinase du récepteur du facteur de croissance épidermique (EGFR-TK), ainsi que leur utilisation dans le traitement de maladies et de troubles associés à la EGFR-TK, notamment le cancer.

Affiliated with

Also associated with

Rating

Quinazoline based egfr inhibitors does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Quinazoline based egfr inhibitors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Quinazoline based egfr inhibitors will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1561731