Quinazoline compounds

Details Quinazoline compounds Quinazoline compounds

C - Chemistry, Metallurgy

07

D

260/253

C07D 417/14 (2006.01) C07D 285/06 (2006.01)

Patent

CA 1121820

SY-1532 ABSTRACT or ABRIDGEMENT A series of novel 4-amino-2-(thiadiazole-carbonyl piperazinyl)-6,7-dimethoxyquinazolines is disclosed having antihypertensive properties. The thiadiazole substituent may be optionally substituted with alkyl or lower alkoxy carbonylamino groups. A representative embodiment of the invention is 4-amino-6,7-dimethoxy-2- [4-(5-ethoxy-carbonylamino-1,2,3-thiadiazole-4-carbonyl)- piperazin-1-y1]-quinazoline.

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