Quinazoline cpompounds

Details Quinazoline cpompounds Quinazoline cpompounds

C - Chemistry, Metallurgy

07

D

C07D 239/94 (2006.01) A61K 31/505 (2006.01) A61K 31/535 (2006.01) C07D 401/04 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 403/00 (2006.01) C07D 405/12 (2006.01) C07D 413/04 (2006.01) C07D 521/00 (2006.01)

Patent

CA 2148260

ABSTRACT It relates to a quinazoline compound useful as a medicine exhibiting an inhibitory action on calmodulin-dependent cGMP-PDE. A quinazoline compound represented by the general formula (I) or a pharmacologically acceptable salt thereof: Image (I) (wherein R1, R2, R3, R4 and R5 may be the same or different from each other and each represents a hydrogen atom, a lower alkyl group or the like; and R6 and R7 may be the same or different from each other and each represents a hydrogen atom, a carboxyl alkyl group or the like). - 91 -

L'invention concerne un composé de quinazoline représenté par la formule générale (I). Ce composé ou de l'un de ses sels utilisables en pharmacie a une action médicamenteuse car il se comporte en inhibiteur de cGMP-PDE calmodulinodépendant. Dans cette formule, R<1>, R<2>, R<3>, R<4> et R<5> représentent chacun indépendamment hydrogène, alkyle inférieur, etc.; R<6> et R<7> représentent chacun indépendamment hydrogène, carboxyalkyle, etc.

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