Quinazoline derivatives

Details Quinazoline derivatives Quinazoline derivatives

C - Chemistry, Metallurgy

07

D

C07D 239/94 (2006.01) A61K 31/498 (2006.01) A61K 31/5377 (2006.01) A61P 35/00 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 403/12 (2006.01) C07D 405/14 (2006.01) C07D 409/12 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2545262

A quinazoline derivative of the Formula (I): wherein the substituents are as defined in the text for use in the production of an anti proliferative effect which effect is produced alone or in part by inhibiting erbB2 receptor tyrosine kinase in a warm-blooded animal such as man.

L'invention concerne un dérivé de quinazoline de formule (I) dans laquelle les substituants sont tels que définis dans le texte, à utiliser dans l'induction d'un effet antiprolifératif, effet produit seul ou en partie par l'inhibition de la tyrosine kinase du récepteur erbB2 chez un animal à sang chaud, tel que l'homme.

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