C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 405/12 (2006.01) A61K 31/517 (2006.01) A61P 35/00 (2006.01) C07D 405/14 (2006.01)
Patent
CA 2419301
The invention concerns quinazoline derivatives of Formula (I) wherein each of m, R1, n, R2 and R3 have any of the meanings defined in the description; processes for their preparation, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use as an anti-invasive agent in the containment and/or treatment of solid tumour disease.
L'invention concerne des dérivés de quinazoline de formule (I) dans laquelle chacun des symboles m, R?1¿, n, R?2¿ et R?3¿ correspond respectivement à une des significations définies dans la description ; des procédés de préparation desdits dérivés, des compositions pharmaceutiques contenant ces dérivés et leur utilisation dans la fabrication d'un médicament utilisé en tant qu'agent anti-invasif pour circonscrire et/ou traiter des maladies à tumeur solide.
Hennequin Laurent Francois Andre
Lambert Christine Marie Paul
Ple Patrick
Astrazeneca Ab
Smart & Biggar
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