Quinazoline derivatives

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 239/94 (2006.01) A61K 31/517 (2006.01) A61P 3/04 (2006.01) C07D 239/95 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 403/04 (2006.01) C07D 405/12 (2006.01)

Patent

CA 2489251

Compounds of formula (I) as well as pharmaceutically acceptable salts and esters thereof, wherein R1, R2, R3 and A have the significance given in claim 1, can be used in the form of pharmaceutical preparations for the treatment or prevention of arthritis, cardiovascular diseases, diabetes, renal failure, eating disorders and obesity.

L'invention concerne des composés représentés par la formule (I), ainsi que des sels pharmaceutiquement acceptables et des esters de ceux-ci. Dans cette formule, R?1¿, R?2¿, R?3¿ et A sont tels que définis dans la revendication 1. Ces composés peuvent être utilisés sous la forme de préparations pharmaceutiques pour le traitement ou la prévention de l'arthrite, des maladies cardiovasculaires, des diabètes, de l'insuffisance rénale, des troubles de l'alimentation et de l'obésité.

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