Quinazoline derivatives

Details Quinazoline derivatives Quinazoline derivatives

C - Chemistry, Metallurgy

07

D

C07D 239/94 (2006.01) A61K 31/517 (2006.01) A61K 31/5377 (2006.01) A61K 31/551 (2006.01) A61P 9/10 (2006.01) A61P 17/06 (2006.01) A61P 35/00 (2006.01) A61P 43/00 (2006.01) C07D 401/06 (2006.01) C07D 401/12 (2006.01) C07D 405/06 (2006.01)

Patent

CA 2442742

Compounds represented by the following general formula (I): (I) pharmaceutically acceptable salts thereof, hydrates or solvates of the same or mixtures of optically active isomers, racemic compounds or diastereomers of the same which have an excellent protein kinase inhibitory activity specific to tyrosine and, therefore, are usable as drugs, in particular, remedies/preventives for various cancers, diseases caused by arteriosclerosis or psoriasis.

L'invention concerne des composés représentés par la formule générale (I), des sels pharmaceutiquement acceptables de ces composés, des hydrates ou des solvates desdits composés ou des mélanges d'isomères optiquement actifs, de composés racémiques ou de diastéréomères desdits composés qui présentent une excellente activité d'inhibition des protéines kinases spécifique à la tyrosine et, de ce fait, peuvent être utilisés comme médicaments, en particulier en traitement/prévention de divers cancers, d'affections liées à l'artériosclérose ou du psoriasis.

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