Quinazoline derivatives

Details Quinazoline derivatives Quinazoline derivatives

C - Chemistry, Metallurgy

07

D

C07D 403/12 (2006.01) A61K 31/517 (2006.01) A61P 35/00 (2006.01) C07D 401/14 (2006.01) C07D 403/14 (2006.01) C07D 405/14 (2006.01) C07D 409/14 (2006.01) C07D 413/14 (2006.01)

Patent

CA 2540008

The invention concerns a quinazoline derivative of the Formula (I): wherein each of the variables have any of the meanings defined in the description; processes for their preparation, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use as an antiproliferative agent in the prevention or treatment of tumours which are sensitive to inhibition of erbB receptor tyrosine kinases.

L'invention concerne des dérivés de quinazoline de formule générale (I), dans laquelle chaque variable a la signification indiquée dans la description ; des procédés de préparation desdits dérivés ; des compositions pharmaceutiques les contenant et leur utilisation dans la production d'un médicament à utiliser en tant qu'agent prolifératif dans la prévention ou le traitement de tumeurs réagissant à l'inhibition des récepteurs tyrosine kinases erbB.

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