Quinazoline derivatives useful for the treatment of...

A - Human Necessities – 61 – K

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A61K 31/505 (2006.01)

Patent

CA 2575512

Use of a therapeutically effective amount of a compound of formula: (see formula I), (see formula II), (see formula III), an equilibrating form thereof, a pharmaceutically acceptable salt of the compound or of the equilibrating form thereof for the treatment of peripheral arterial disease or for inhibiting phosphodiesterase in a subject, wherein R1 is H, C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, C1-6 alkoxy, or C6-10 aryl; R2 is -C(O)H or -CH(OH)2; R3 is OH, Halogen, SH, O-C1-6 alkyl or NH2; and X and Y are independently H or halogen.

La présente invention concerne une méthode de traitement des maladies artérielles périphériques chez un hôte qui consiste à administrer une quantité efficace du point de vue thérapeutique de composés représentés par les formules (I) à (III) ou bien d'analogues de ces composés.

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