C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 239/94 (2006.01) A61K 31/495 (2006.01) C07D 401/04 (2006.01) C07D 401/12 (2006.01) C07D 403/04 (2006.01) C07D 403/12 (2006.01) C07D 405/12 (2006.01) C07D 409/12 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01)
Patent
CA 2615380
The present invention provides compounds of Formula I (wherein X, m, R1, R2, R3, and R4 are as defined herein), or a pharmaceutically acceptable salt, solvate or ester thereof. The present invention also provides compositions comprising these compounds that are useful for treating cellular proliferative diseases, disorders associated with activity of mutants of p53, or in causing apoptosis of cancer cells.
La présente invention concerne des composés de formule I (dans laquelle X, m, R1, R2, R3, et R4 sont tels que définis dans l'invention), ou un sel, solvate ou ester de ceux-ci, acceptable d'un point de vue pharmaceutique. L'invention a également pour objet des compositions comprenant ces composés, utiles pour traiter des troubles de prolifération cellulaire, des troubles associés à l'activité de formes mutantes de p53, ou pour provoquer l'apoptose de cellules cancéreuses.
Dasmahapatra Bimalendu
Demma Mark
Mallams Alan K.
Neustadt Bernard R.
Vaccaro Henry A.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Schering Corporation
LandOfFree
Quinazoline derivatives useful in cancer treatment does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Quinazoline derivatives useful in cancer treatment, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Quinazoline derivatives useful in cancer treatment will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-2085329