Quinazolines for pdk1 inhibition

Details Quinazolines for pdk1 inhibition Quinazolines for pdk1 inhibition

C - Chemistry, Metallurgy

07

D

C07D 239/84 (2006.01) A61K 31/517 (2006.01) A61P 35/00 (2006.01) C07D 401/08 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 403/04 (2006.01) C07D 403/06 (2006.01) C07D 403/12 (2006.01) C07D 411/04 (2006.01) C07D 413/14 (2006.01) C07D 417/04 (2006.01)

Patent

CA 2673003

The invention provides novel compounds that are inhibitors of PDK1. Also provided are pharmaceutical compositions including the compounds, and methods of treating proliferative diseases, such as cancers, with the compounds or compositions.

Cette invention concerne de nouveaux composés qui sont des inhibiteurs de PDK1. Elle concerne également des compositions pharmaceutiques contenant ces composés, et des méthodes utilisant ces composés et compositions pour le traitement de maladies à évolution chronique comme le cancer.

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