Quinazolines useful as modulators of ion channels

Details Quinazolines useful as modulators of ion channels Quinazolines useful as modulators of ion channels

C - Chemistry, Metallurgy

07

D

C07D 239/94 (2006.01) A61K 31/517 (2006.01) C07D 401/04 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 403/04 (2006.01) C07D 403/12 (2006.01) C07D 403/14 (2006.01) C07D 405/12 (2006.01) C07D 409/12 (2006.01) C07D 409/14 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01) C07D 417/14 (2006.01) C07D 471/04 (2006.01)

Patent

CA 2517844

The present invention relates to quinazoline compounds of formula (I) useful as inhibitors of voltage-gated sodium channels and calcium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders. or a pharmaceutically acceptable derivative thereof, wherein R1, X, R3, x, and ring A are as defined in the present application.

La présente invention concerne des composés utilisés comme inhibiteurs de canaux sodiques et calciques dépendants du potentiel d'action. La présente invention concerne également des compositions acceptables d'un point de vue pharmaceutique qui comprennent ces composés, ainsi que des procédés pour utiliser ces compositions afin de traiter divers troubles.

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