A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/517 (2006.01)
Patent
CA 2504388
The present invention relates to pharmaceutical compositions for modifying gene expression in a pathological process, thereby preventing or ameliorating said process. More particularly the compositions comprise quinazolinones, especially halofuginone, for inhibiting or preventing alterations in gene expression during fibrosis. The present invention particularly relates to pharmaceutical compositions for improving the regeneration of cirrhotic liver.
La présente invention concerne des compositions pharmaceutiques pouvant modifier l'expression génétique dans un processus pathologique, pour empêcher ou améliorer ledit processus. Plus particulièrement, les compositions de l'invention comprennent des quinazolinones, en particulier l'halofuginone, destinés à inhiber ou empêcher des modifications de l'expression génétique pendant la cirrhose. L'invention concerne en particulier des compositions pharmaceutiques pouvant améliorer la régénération d'un foie atteint de cirrhose.
Nagler Arnon
Pines Mark
Vlodavsky Israel
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Collgard Biopharmaceuticals Ltd.
Hadasit Medical Research Services And Development Ltd.
State Of Israel Ministry Of Agriculture
LandOfFree
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