A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/517 (2006.01) A61K 45/06 (2006.01) A61P 35/00 (2006.01) C07D 239/88 (2006.01)
Patent
CA 2472160
The present invention provides compositions and methods for improving the effectiveness of anti-tumor treatments. The compositions of the present invention comprise quinazolinones, specifically halofuginone. In currently preferred embodiments the compositions and methods of the present invention improve the effectiveness of radiation therapy and chemotherapy, and concomitantly alleviate or prevent the damage induced by radiation therapy.
L'invention concerne des compositions et des méthodes permettant d'améliorer l'efficacité de traitements antitumoraux. Ces compositions comprennent des quinazolinones, en particulier de l'halofuginone. Dans des modes de réalisation actuellement préférés, les compositions et les méthodes de l'invention permettent d'améliorer l'efficacité d'une radiothérapie et d'une chimiothérapie, et de soulager simultanément ou de prévenir des lésions provoquées par une radiothérapie.
Nagler Arnon
Pines Mark
Vlodavsky Israel
Yarkoni Shai
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Collgard Biopharmaceuticals Ltd.
Hadasit Medical Research Services And Development Ltd.
Institute Of Animal Science Agricultural Research Org.
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