A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/445 (2006.01) A61K 31/505 (2006.01) A61K 31/517 (2006.01)
Patent
CA 2280850
The invention provides a composition for attenuating neovascularization and treating malignancies, including a pharmaceutically effective amount of a compound having a formula (I) (See formula I) wherein; R1 is a member of the group consisting of hydrogen, halogen, nitro, benzo, lower alkyl, phenyl and lower alkoxy; R2 is a member of the group consisting of hydroxy, acetoxy, and lower alkoxy, and R3 is a member of the group consisting of hydrogen and lower alkenoxy carbonyl; and pharmaceutically acceptable salts thereof; as active ingredient therein, in combination with a pharmaceutically acceptable carrier.
L'invention concerne une composition destinée à atténuer la néoformation de vaisseaux sanguins et à traiter des affections malignes, et comprenant une dose efficace sur le plan pharmacologique d'un composé correspondant à la formule (I), ou de sels de celui-ci, acceptables sur le plan pharmacologique. Dans cette formule R1 est choisi dans le groupe constitué par hydrogène, halogène, nitro, benzo, alkyle inférieur, phényle et alcoxy inférieur, R2 est choisi dans le groupe constitué par hydroxy, acétoxy et alcoxy inférieur, et R3 est choisi dans le groupe constitué par hydrogène et alcénoxy inférieur-carbonyle. L'invention concerne l'utilisation de cette composition en tant que principe actif, en combinaison avec un excipient acceptable sur le plan pharmacologique.
Miao Hua-Quan
Nagler Arnon
Pines Mark
Vlodavsky Israel
Agricultural Research Organization Ministry Of Agriculture
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Hadasit Medical Research Services & Development Company Ltd.
Hadasit Medical Research Services And Development Company Ltd.
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