C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 239/82 (2006.01) A61K 31/517 (2006.01) A61P 25/00 (2006.01)
Patent
CA 2600868
The present invention is directed to quinazolinone compounds which are antagonists of T-type calcium channels, and which are useful in the treatment or prevention of disorders and diseases in which T-type calcium channels are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which T-type calcium channels are involved.
L'invention concerne des composés de quinazolinone qui sont des antagonistes de canaux calciques de type T, et qui sont utilisés pour traiter ou prévenir des troubles ou des maladies dans lesquels les canaux calciques de type T sont impliqués. L'invention concerne également des compositions pharmaceutiques comprenant lesdits composés, et l'utilisation de ces composés et compositions pour prévenir ou traiter des maladies dans lesquelles les canaux calciques de type T sont impliqués.
Barrow James C.
Cube Rowena V.
Ngo Phung Le
Rittle Kenneth E.
Yang Zhiqiang
Merck & Co. Inc.
Merck Sharp & Dohme Corp.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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