C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/06 (2006.01) A61K 31/517 (2006.01) A61P 25/04 (2006.01) A61P 25/08 (2006.01) A61P 25/20 (2006.01) C07D 239/82 (2006.01) C07D 413/06 (2006.01)
Patent
CA 2692783
The present invention is directed to quinazolinone compounds which are antagonists of T-type calcium channels, and which are useful in the treatment or prevention of disorders and diseases in which T-type calcium channels are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which T-type calcium channels are involved.
La présente invention concerne des composés de quinazolinone qui sont des antagonistes des canaux calciques de type T, et qui sont utiles dans le traitement ou la prévention de troubles et de maladies dans lesquels des canaux calcique de type T sont impliqués. L'invention concerne également des compositions pharmaceutiques comprenant ces composés, et l'utilisation de ces composés et de ces compositions dans la prévention ou le traitement des maladies dans lesquelles des canaux calciques de type T sont impliqués.
Barrow James C.
Yang Zhi-Qiang
Merck Sharp & Dohme Corp.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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