Quiniclidine derivatives of (hetero)...

C - Chemistry – Metallurgy – 07 – D

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C07D 453/02 (2006.01) A61K 31/439 (2006.01)

Patent

CA 2669326

The invention provides compounds of formula (I) wherein R4 is a group of formula (II) or (IIIa) or (IIIb) and R1, R2, R3, R5, a, b and X are as defined in the specification, a process for their preparation, pharmaceutical compositions containing them, a process for preparing pharmaceutical compositions, their use in therapy and intermediates of use in their preparation (I), (II), (IIIa), (IIIb).

L'invention concerne des composés représentés par la formule (I) dans laquelle R4 représente un groupe de formule (II) ou (IIIa) ou (IIIb) et R1, R2, R3, R5, a, b et X correspondent à leur définition dans le descriptif, un procédé servant à les préparer, des compositions pharmaceutiques les contenant, un procédé servant à préparer ces compositions pharmaceutiques, leur utilisation thérapeutique, ainsi que des intermédiaires à leur préparation (I), (II), (IIIa), (IIIb).

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