(quinolin-2-ylmethoxy) indole/cyclodextrin complex

Details (quinolin-2-ylmethoxy) indole/cyclodextrin complex (quinolin-2-ylmethoxy) indole/cyclodextrin complex

C - Chemistry, Metallurgy

08

B

C08B 37/16 (2006.01) A61K 31/715 (2006.01) A61K 47/48 (2006.01) C07D 401/12 (2006.01)

Patent

CA 2082777

A complex of cyclodextrin and 3-[N-(p-chlorobenzyl)-3-(t-butylthio)-5-(quinolin-2- ylmethoxy)indol-2-yl]-2,2-dimethylpropanoic acid, sodium salt is more soluble in water than the sodium salt alone. The complex is useful as an anti- asthmatic, anti-allergic, anti-inflammatory, or cytoprotective agent. It is also useful in treating diarrhea, hypertension, angina, platelet aggregation, cerebral spasm, premature labor, spontaneous abortion, dysmenorrhea, and migraine.

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