Quinoline-2-carboxylic acid derivative and its use as...

C - Chemistry – Metallurgy – 07 – D

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C07D 215/48 (2006.01) A61K 31/47 (2006.01) C07B 57/00 (2006.01)

Patent

CA 2284710

The (+) enantiomer of E 4-(4-Acetylamino-phenylcarbamoylmethylene)-5,7- dichloro-1,2,3,4-tetrahydro quinoline 2-carboxylic acid and salt thereof which are antagonist of excitatory amino acids, to processes for their preparation, to pharmaceutical compositions containing them, and to their use in medicine.

Enantiomère (+) d'acide E 4-(4-acétylamino-phénylcarbamoyl-méthylène)-5,7-dichloro-1,2,3,4-tétrahydroquinoléine 2-carboxylique et ses sels antagonistes d'acides aminés excitateurs, procédés servant à les préparer, compositions pharmaceutiques les contenant et leur utilisation en médecine.

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