Quinoline and quinazoline derivatives as ligands for the...

C - Chemistry – Metallurgy – 07 – D

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C07D 215/42 (2006.01) A61K 31/4706 (2006.01) A61K 31/517 (2006.01) A61P 3/00 (2006.01) C07D 239/84 (2006.01) C07D 401/04 (2006.01) C07D 401/14 (2006.01) C07D 409/04 (2006.01) C07D 409/14 (2006.01)

Patent

CA 2420703

Compounds of formula (I) as well as pharmaceutically usable salts, solvates and esters thereof, wherein R1, R2, R3, R4, A1 and A2 have the significance given in claim 1, can be used in the form of pharmaceutical preparations for the treatment or prevention of arthritis, cardiovascular diseases, diabetes, renal failure, eating disorders and obesity.

Selon l'invention, les composés de la formule, dans laquelle R?1¿, R?2¿, R?3¿, R?4¿, A?1¿ et A?2¿ ont la signification donnée dans la revendication 1, ainsi que des sels, solvates et esters utilisables dans le domaine pharmaceutique, peuvent être utilisés sous forme de préparations pharmaceutiques destinées au traitement ou à la prévention de l'arthrite, des maladies cardio-vasculaires, du diabète, de l'insuffisance rénale, des troubles alimentaires et de l'obésité.

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