A - Human Necessities – 61 – L
Patent
A - Human Necessities
61
L
A61L 31/16 (2006.01) A61K 31/47 (2006.01) A61K 31/498 (2006.01) A61L 31/10 (2006.01) A61P 9/10 (2006.01)
Patent
CA 2352584
This invention is directed to quinoline/quinoxaline compounds which inhibit platelet-derived growth factor tyrosine kinase and/or Lck tyrosine kinase, to pharmaceutical compositions comprising these compounds, and to the use fo these compounds for treating a patient suffering from or subject to disorders/conditions involving cellular differentiation, proliferation, extracellular matrix production or mediator release and/or T cell activation and proliferation.
La présente invention concerne des composés de quinoline et de quinoxaline qui bloquent le facteur de croissance d'origine plaquettaire ou l'activité tyrosine kinase du Lck. L'invention concerne également, d'une part des compositions pharmaceutiques comprenant ces composés, et d'autre part l'utilisation de ces composés pour traiter un patient souffrant ou sujet à des troubles ou à des états imputables à des problèmes de différenciation cellulaire, de prolifération cellulaire, de production de matrice extracellulaire, ou de libération de médiateur et/ou d'activation et prolifération de lymphocytes T.
Maguire Martin P.
Myers Michael R.
Persons Paul E.
Spada Alfred P.
Aventis Pharmaceuticals Inc.
Aventis Pharmaceuticals Products Inc.
Deeth Williams Wall Llp
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