C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/04 (2006.01) A61K 31/4709 (2006.01) A61P 35/00 (2006.01) C07D 487/04 (2006.01) C07D 519/00 (2006.01)
Patent
CA 2691529
The present invention relates to novel quinoline compounds of the formula (I) and to the salts thereof. The com-pounds possess valuable therapeutic properties and are particu-larly suitable, for treating diseases that respond to modulation of the serotonin 5-HT6 receptor. In formula (I) R is a moiety of the formula (R) wherein * indicates the binding site to the quinolinyl radical and wherein A, B, X', Y, Q, R1, R2, R3, R4, R5, m, n, p, q, R a, R b, X and Ar are as defined in claim 1.
Cette invention se rapporte à de nouveaux composés de quinoléine de formule (I) et à leurs sels. Les composés manifestent des propriétés thérapeutiques précieuses et sont particulièrement adaptés pour traiter les affections sensibles à la modulation des récepteurs sérotoninergiques 5-HT6. Dans la formule (I), R est une fraction de la formule (R) où * indique le site de fixation au radical quinolinyle et où A, B, X', Y, Q, R1, R2, R3, R4, R5, m, n, p, q, Ra, Rb, X et Ar sont tels que définis selon la revendication 1.
Braje Wilfried
Drescher Karla
Haupt Andreas
Lange Udo
Mayrer Matthias
Abbott Gmbh & Co. Kg.
Torys Llp
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