C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/04 (2006.01) A61K 31/47 (2006.01) A61K 31/4709 (2006.01) C07D 215/14 (2006.01) C07D 215/227 (2006.01) C07D 215/38 (2006.01) C07D 401/06 (2006.01) C07D 401/10 (2006.01) C07D 401/12 (2006.01) C07D 405/04 (2006.01) C07D 405/06 (2006.01) C07D 405/10 (2006.01) C07D 405/12 (2006.01) C07D 405/14 (2006.01) C07D 409/04 (2006.01) C07D 409/10 (2006.01) C07D 409/14 (2006.01)
Patent
CA 2553269
The present invention relates to novel substituted quinoline derivatives according to the general Formula (Ia) or the general Formula (Ib) the pharmaceutically acceptable acid or base addition salts thereof, the quaternary amines thereof, the stereochemically isomeric forms thereof, the tautomeric forms thereof and the N-oxide forms thereof. The claimed compounds are useful for the treatment of mycobacterial diseases.
La présente invention concerne des nouveaux dérivés de quinoline substitués représentés par la formule générale (Ia) ou par la formule générale (Ib), les sels d'addition de base ou acides pharmaceutiquement acceptables de ceux-ci, les amines quaternaires de ceux-ci, les formes isomères stéréochimiques de ceux-ci, les formes tautomériques de ceux-ci et les forme N-oxyde de ceux-ci. Les composés décrits dans cette invention sont utiles pour le traitement de maladies mycobactériennes.
Guillemont Jerome Emile Georges
Lancois David Francis Alain
Pasquier Elisabeth Therese Jeanne
Gowling Lafleur Henderson Llp
Janssen Pharmaceutica N.v.
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