Quinoline derivatives as antibacterial agents

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 215/227 (2006.01) A61K 31/47 (2006.01) A61P 31/04 (2006.01) C07D 215/36 (2006.01)

Patent

CA 2612623

Use of a compound for the manufacture of a medicament for the treatment of a bacterial infection provided that the bacterial infection is other than a Mycobacterial infection, said compound being a compound of formula (Ia) or (Ib) a pharmaceutically acceptable acid or base addition salt thereof, a stereochemically isomeric form thereof, a tautomeric form thereof or a N-oxide form thereof. Several of these compounds are also claimed as such. Further the combination of the above compounds with other antibacterial agents is described

La présente invention décrit l'emploi d'un composé dans la fabrication d'un médicament pour le traitement d'une infection bactérienne, à la condition que ladite infection bactérienne soit différente d'une infection mycobactérienne, ledit composé étant un composé de formule (Ia) ou (Ib) un sel d'addition acide ou basique de qualité pharmaceutique de ce composé, une forme isomère stéréochimique de ce composé, une forme tautomère de ce composé ou un N-oxyde de ce composé. Plusieurs de ces composés sont également revendiqués eux-mêmes par l'invention. La présente invention décrit également la combinaison desdits composés avec d'autres agents antibactériens.

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