Quinoline derivatives as axl kinase inhibitors

Details Quinoline derivatives as axl kinase inhibitors Quinoline derivatives as axl kinase inhibitors

C - Chemistry, Metallurgy

07

D

C07D 215/20 (2006.01) A61K 31/407 (2006.01) A61K 31/4709 (2006.01) A61K 31/506 (2006.01) C07D 401/12 (2006.01) C07D 405/12 (2006.01) C07D 409/12 (2006.01) C07D 413/12 (2006.01)

Patent

CA 2718538

The present invention relates to novel compounds which are inhibitors of receptor tyrosine kinases of the AXL receptor family. These compounds are suitable for the treatment or prevention of disorders associated with, accompanied by or caused by hyperfunction of a receptor of the AXL family. The compounds are suitable for the treatment of hyperproliferative disorders, such as cancer, particularly cancer metastases. Image

Cette invention concerne de nouveaux composés qui sont des inhibiteurs des tyrosine kinases réceptrices de la famille des récepteurs AXL. Ces composés peuvent être utilisés pour traiter ou prévenir les troubles associés à l'hyperfonction d'un récepteur de la famille des AXL, ou accompagnés ou provoqués par une telle hyperfonction. Les composés peuvent être utilisés pour traiter les troubles hyperprolifératifs, tels que le cancer, en particulier les métastases cancéreuses.

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